Seven in ten researchers have failed to reproduce someone else’s result.

Nature survey of 1,576 researchers. In biology the figure is higher than in any other field. Baker, M. 1,500 scientists lift the lid on reproducibility. Nature 533, 452-454 (2016).

Scroll

We check the evidence, not the science

Kelvara does not predict, design, or discover. Each agent answers one narrow question about whether published evidence supports something you are about to rely on: a reagent, a sequence, a target, a claim.

That is a smaller job than most tools in this field claim, and it is the job we can do honestly without a wet lab behind us.

Every agent reports what it could not establish. Which sources were unreachable, which dimensions had no evidence either way, and what the verdict does not cover. The limits block is mandatory and never empty.

Accuracy is published with confidence intervals against named benchmark datasets, including the cases we get wrong. If an agent cannot answer, it says so rather than guessing.

Pick the one that matches your week

6 agents
Antiagent

Is this antibody validated for the application you're using it for?

Live opens in a new tab
Foldamer

Will this peptide aggregate, degrade, or fail to cross a membrane?

Live opens in a new tab
Target Watch

What changed in the literature and trials on your target this week?

Beta opens in a new tab
Lapsis

What was filed, and what lapsed, in your technology area?

Building
Biomarker Readiness

Does this biomarker have the evidence its intended use requires?

Building
Analysis Audit

Does your RNA-seq pipeline contain a known method failure?

Planned

How to check us

Three things you can read before trusting a single verdict.

Grading method

What each evidence tier means, per agent, and the rules that move a result from one tier to the next.

Read the method

Benchmarks

Accuracy against named public datasets with Wilson score confidence intervals, and the disagreement rate on cases we call wrong.

See the numbers

Sources and licences

Every database we query, its licence, the date it was checked, and whether commercial use and caching are permitted.

See the sources

Free while we find out what's useful. Source code and benchmark method are public.